Measuring Type 1/Type 2 Immunity

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  • Forsthuber, T., H.C. Yip, and P.V. Lehmann. 1996. Induction of TH1 and TH2 immunity in neonatal mice. Science. 271: 1728-1730.
  • Chu, R.S., O.S. Targoni, A.M. Krieg, P.V. Lehmann, and C.V. Harding. 1997. CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J. Exp. Med. 186: 1623-1631.
  • Yip, H.C., A.Y. Karulin, M. Tary-Lehmann, M.D. Hesse, H. Radeke, P. Heeger, R.T. Trezza, F.P. Heinzel, T. Forsthuber, and P.V. Lehmann. 1999. Adjuvant guided type 1 and type 2 immunity: Infectious/non-infectious dichotomy defines the class of response. J. Immunol. 162: 3942-3949.
  • Karulin, A.Y., M.D. Hesse, H.C. Yip, and P.V. Lehmann. 2002. Indirect IL-4 pathway in Th1 immunity. J. Immunol. 168: 545-553.
  • Guerkov, R.E., O.S. Targoni, C.R. Kreher, B.O. Boehm, M.T. Herrera, M. Tary-Lehmann, P.V. Lehmann, and S.K. Schwander. 2003. Detection of low-frequency antigen-specific IL-10-producing CD4(+) T cells via ELISPOT in PBMC: cognate vs. nonspecific production of the cytokine. J. Immunol. Methods. 279: 111-121.