Transplantation Immunology

  • Lehmann, P.V., and P. Heeger. 1997. Induction of Th1 or Th2 immunity to immunodominant indirect pathway peptide. Transplantation. 64: 292-96.
  • Lehmann, P. V., K. Drexler, M. Tary-Lehmann, F. Falcioni, U. Hurtenbach, and Z. A. Nagy. 1991. Graft-versus-host resistance induced by class II major histocompatibility complex-specific T cell clones. J. Exp. Med. 173:333.
  • Lehmann, P. V., G. Schumm, D. Moon, U. Hurtenbach, F. Falcioni, S. Muller, and Z. A. Nagy. 1990. Acute lethal graft-versus-host reaction induced by major histocompatibility complex class II-reactive T helper cell clones. J. Exp. Med. 171:1485.
  • Matesic, D., P.V. Lehmann, and P.S. Heeger. 1998. High-resolution characterization of cytokine producing alloreactivity in naive and allograft primed mice. Transplantation. 65: 906-914.
  • Tary-Lehmann, M., D. Hricik, A. C. Justice, N. S. Potter and P.S. Heeger. 1998. Enzyme-linked immunosorbent assay spot detection of interferon-γ and interleukin 5 producing cells as a predictive marker for renal allograft failure. Transplantation. 66: 219-224.
  • Tary-Lehmann, M., A. Saxon, and P. V. Lehmann. 1995. The human immune system in hu-PBL-SCID mice. Immunol. Today 16:529.
  • Tary-Lehmann, M., P. V. Lehmann, D. Schols, M. G. Roncarolo, and A. Saxon. 1994. Anti-SCID mouse reactivity shapes the human CD4+ T cell repertoire in hu-PBL-SCID chimeras. J. Exp. Med. 180:1817.
  • Tary-Lehmann, M., and A. Saxon. 1992. Human mature T cells that are anergic in vivo prevail in SCID mice reconstituted with human peripheral blood. J. Exp. Med. 175:503.
  • Tary-Lehmann, M., A. G. Rolink, P. V. Lehmann, Z. A. Nagy, and U. Hurtenbach. 1990. Induction of graft versus host-associated immunodeficiency by CD4+ T cell clones. J. Immunol. 145:2092.
  • Heeger, P.S., N. Greenspan, S. Kuhlenschmidt, C. Dejelo, D.E. Hricik, J. Schulak and M. Tary-Lehmann. 1999. Pretransplant frequency of donor specific, IFN-γ producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J. Immunology. 163: 2267-2275.
  • Heeger, P. S., T. Forsthuber, C. Shive, E. Biekert, C. Genain, H. H. Hofstetter, A. Karulin, and P. V. Lehmann. 2000. Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant. J. Immunol. 164:5771. <abstract>
  • Heeger, P.S., A. Valujskih and P.V. Lehmann. 2000. Comprehensive assessment of determinant specificity, frequency, and cytokine signature of the primed CD8 cell repertoire induced by a minor transplantation antigen. J. Immunol. 165: 1278-1284.
  • Gebauer, B.S., D.E. Hricik, A. Atallah, K. Bryan, J. Riley, M. Tary-Lehmann, N.S. Greenspan, B.O. Boehm, B.J. Hering and P.S. Heeger. 2002. Evolution of the Enzyme-Linked Immunosorbent Spot Assay for Post-Transplant Alloreactivity as a Potentially Useful Immunme Monitoring Tool. The American Journal of Transplantation. 9: 857-866.
  • Hricik, D. E., V. Rodriguez, J. Riley, K. Bryan, M. Tary-Lehmann, N. Greenspan, C. Dejelo,J. A. Schulak, and P.S Heeger. 2003. Enzyme linked immunosorbent spot (ELISPOT) assay for Interferon-γ independently predicts renal function in kidney transplant recipients. Am. J. Transplantation. 7: 878-884.
  • Kleen, T. O., S. Kadereit, L. R. Fanning, J. Jaroscak, P. Fu, H. J. Meyerson, L. Kulchycki, L. F. Slivka, M. Kozik, M. Tary-Lehmann, and M. J. Laughlin. 2005. Recipient-specific tolerance after HLA-mismatched umbilical cord blood stem cell transplantation. Transplantation 80:1316.
  • Kadereit, S., G. R. Junge, T. Kleen, M. M. Kozik, B. A. Kaminski, K. um-Woods, P. Fu, M. Tary-Lehmann, and M. J. Laughlin. 2003. Deficient IFN-gamma expression in umbilical cord blood (UCB) T cells can be rescued by IFN-gamma-mediated increase in NFATc2 expression. J. Clin. Immunol. 23:485.
  • Baron, E. D., P. S. Heeger, D. E. Hricik, J. A. Schulak, M. Tary-Lehmann, and S. R. Stevens. 2001. Immunomodulatory effect of extracorporeal photopheresis after successful treatment of resistant renal allograft rejection. Photodermatol. Photoimmunol. Photomed. 17:79
  • Lehmann, P. V., D. Matesic, G. Benichou, and P. S. Heeger. 1997. Induction of T helper 2 immunity to an immunodominant allopeptide. Transplantation 64:292
  • Lehmann, P. V. 1996. Immunomodulation by proteolytic enzymes. Nephrol. Dial. Transplant. 11:952.
  • Benichou, G., E. Fedoseyeva, P. V. Lehmann, C. A. Olson, H. M. Geysen, M. McMillan, and E. E. Sercarz. 1994. Limited T cell response to donor MHC peptides during allograft rejection. Implications for selective immune therapy in transplantation. J. Immunol. 153:938.
  • Saxon, A., E. Macy, K. Denis, M. Tary-Lehmann, O. Witte, and J. Braun. 1991. Limited B cell repertoire in severe combined immunodeficient mice engrafted with peripheral blood mononuclear cells derived from immunodeficient or normal humans. J. Clin. Invest 87:658.